Uses of Dapoxetine+Tadalafil

The combination of Dapoxetine + Tadalafil is used to improve blood supply to the penis and facilitate an erection.

Therapeutic Category

Dapoxetine: Selective serotonin reuptake inhibitors

Tadalafil: Phosphodiesterase type 5 (PDE5) inhibitors

How Dapoxetine+Tadalafil works

Dapoxetine is a selective serotonin reuptake inhibitor. It is believed to promote control over penile function by increasing the activity of a particular chemical called serotonin in the brain. Tadalafil is a PDE5 inhibitor. It relaxes the blood vessels supplying the penis which allows increased blood and oxygen supply, thereby improving its erection properties.

Common side effects of Dapoxetine+Tadalafil

• dizziness, headache
• back pain, muscle pain, pain in arms and legs
• nausea, vomiting
• feeling irritable, anxious, agitated, or restless
• sensation of numbness, tingling or prickling
• increased sweating
• hot flushes
• diarrhea, constipation, wind, stomach pain, indigestion
• problems in sleeping or strange dreams, difficulty in concentration
• tiredness or sleepiness
• blocked nose
• a rise in blood pressure
• decrease in sex drive
• ringing in the ears
• blurred vision, color tinge to vision, visual disturbance
• dry mouth

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• chest pain
• sudden decline or loss of vision
• fits or seizures
• fainting or light headedness while standing
• mood changes, suicidal thoughts, or a tendency for self-harming

Health Tips for Dapoxetine+Tadalafil

• Take Dapoxetine + Tadalafil preferably before meals. Follow the dosing schedule as advised by your physician. Do not take this medicine for a longer period than advised by your doctor
• Avoid taking Dapoxetine + Tadalafil with grapefruit juice, as it may reduce the effectiveness of this medicine or may create unpleasant side effects
• Dapoxetine + Tadalafil can cause excessive dizziness or drowsiness. Therefore, do not drive or perform any activities that require complete concentration. Avoid consumption of alcohol as it could aggravate your dizziness
• Before taking this medicine, inform your doctor if you have any previous history of fainting or dizziness due to low blood pressure
• You must also inform your doctor if you have epilepsy, lung problems, mental health problems, or bleeding disorders as a precaution

I'm a 13 year old female who has a chronic erectile dysfunction that makes it difficult for her to achieve an erection. She is currently not taking the effect of low dose tadalafil. She does not have a previous libido problem but she feels that there is no reason to be extra shy about sharing her story. Her husband and her family are in Dubai and she's not sure whether she'd be able to relate back. What does your doctor call this? It means that the effect of low dose tadalafil has been missed and it's time to consult your doctorDapoxetine+Tadalafil 10M+Tadalafil 30M+ViagraHow it’s done

This medicine is available only with a doctor's prescription.

What is Dapoxetine?

Dapoxetine is a prescription-only medicine used to improve blood flow to the penis. It is not recommended for use in women or children. It is not recommended for use in pregnancy. Do not take Dapoxetine if you are pregnant or planning to become pregnant, or if you are breastfeeding.

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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Here are the key drug-food Interactions to be aware of:

1. : Though not a direct interaction, combining Cialis with high Cialis intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
2. : Grapefruit can increase the levels of tadalafil by interfering with its metabolism by inhibiting 5-alpha reductase (RAX), the enzyme that converts tadalafil to its active metabolite. This may amplify side effects, such as headaches or dizziness.